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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
14.24
Human Site:
S532
Identified Species:
24.1
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S532
N
I
D
V
N
I
N
S
Q
E
E
V
V
K
L
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S532
N
I
D
V
N
I
N
S
Q
E
E
V
V
K
L
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
I526
N
L
E
K
D
I
N
I
Q
E
E
V
V
K
L
Dog
Lupus familis
XP_532028
914
101864
K620
A
L
H
I
N
I
N
K
A
E
E
K
K
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
S531
T
I
D
I
N
V
N
S
Q
E
E
V
V
K
L
Rat
Rattus norvegicus
Q5FVG2
731
81700
S531
A
I
D
I
N
V
N
S
Q
E
E
V
V
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
P532
R
F
P
S
N
P
N
P
P
D
Q
P
H
V
P
Chicken
Gallus gallus
XP_422083
502
57358
D304
H
T
F
V
F
R
L
D
H
P
K
A
C
K
H
Frog
Xenopus laevis
NP_001080234
498
57093
V300
K
E
Q
E
H
T
F
V
F
K
M
D
H
P
K
Zebra Danio
Brachydanio rerio
O57457
619
70690
S421
P
Q
S
G
L
Y
N
S
A
S
E
R
N
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
N709
S
S
N
M
H
T
S
N
T
N
S
S
N
N
H
Honey Bee
Apis mellifera
XP_623974
809
90976
N611
M
D
T
P
T
V
I
N
K
N
N
Q
H
S
D
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
N733
R
V
A
D
S
V
P
N
S
D
K
L
S
K
S
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
V534
N
T
A
S
R
A
T
V
S
A
S
M
L
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
66.6
33.3
N.A.
80
80
N.A.
13.3
13.3
0
26.6
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
86.6
46.6
N.A.
93.3
93.3
N.A.
26.6
26.6
13.3
26.6
N.A.
40
20
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
0
0
8
0
0
15
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
29
8
8
0
0
8
0
15
0
8
0
0
8
% D
% Glu:
0
8
8
8
0
0
0
0
0
43
50
0
0
0
0
% E
% Phe:
0
8
8
0
8
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
8
0
15
0
0
0
8
0
0
0
22
0
15
% H
% Ile:
0
29
0
22
0
29
8
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
0
8
8
8
15
8
8
58
8
% K
% Leu:
0
15
0
0
8
0
8
0
0
0
0
8
8
0
36
% L
% Met:
8
0
0
8
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
29
0
8
0
43
0
58
22
0
15
8
0
15
8
0
% N
% Pro:
8
0
8
8
0
8
8
8
8
8
0
8
0
8
8
% P
% Gln:
0
8
8
0
0
0
0
0
36
0
8
8
0
8
8
% Q
% Arg:
15
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
8
8
15
8
0
8
36
15
8
15
8
8
8
22
% S
% Thr:
8
15
8
0
8
15
8
0
8
0
0
0
0
0
0
% T
% Val:
0
8
0
22
0
29
0
15
0
0
0
36
36
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _